Local Anesthetic Powder Levobupivacaine Hydrochloride/Levobupivacaine HCI 27262-48-2

Model NO.: 27262-48-2
CAS: 27262-48-2
MF: C18H29ClN2O
MW: 324.89
Packing: as required
Appearance: White crystalline powder
Trademark: yuancheng
Transport Package: Foil Bag
Specification: 99%
Origin: Wuhan
HS Code: 3002100000
Model NO.: 27262-48-2
CAS: 27262-48-2
MF: C18H29ClN2O
MW: 324.89
Packing: as required
Appearance: White crystalline powder
Trademark: yuancheng
Transport Package: Foil Bag
Specification: 99%
Origin: Wuhan
HS Code: 3002100000
Levobupivacaine Hydrochloride


Basic Information: 
Synonyms: BUPIVACAINE HCL; (S)-Bupivacaine; LEVAMISOLHCLSALT; L-(-)-Bupivacaine; TIMTEC-BB SBB001337; LEVOBUPIVACAINE HCL; (S)-(-)-Bupivacaine; (S)-(-)-BUPIVACAINE HCL; bupicainehydrochloride(-); L-BUPIVACAINE HYDROCHLORIDE

Product Name: Levobupivacaine Hydrochloride
AS No.: 27262-48-2
Packing: 25kg/drum
M.F.: C18H29ClN2O
M.W.: 324.8887
Appearance: White crystalline powder




Additional Information:
product categories: Pharmaceutical raw materials; Active pharmaceutical ingredients
usage: Anesthetic; Na+ channel inhibitor.
Storage instructions: Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Packaging details: 25kg/drum, 1kg/foil bag
Delivery time: 1-2 days
Payment terms: T/T, western union, money gram, bitcoin



Description:
The hydrochloride salt of levobupivacaine, an amide derivative with anesthetic property. Levobupivacaine reversibly binds voltage-gated sodium channels to modulate ionic flux and prevent the initiation and transmission of nerve impulses (stabilizing neuronal membrane), thereby resulting in analgesia and anesthesia. In comparison with racemic bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action.

Levobupivacaine (rINN) is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine. It is the hydrochloride salt of levobupivacaine, an amide derivative with anesthetic property.

Levobupivacaine reversibly binds voltage-gated sodium channels to modulate ionic flux and prevent the initiation and transmission of nerve impulses (stabilizing neuronal membrane), thereby resulting in analgesia and anesthesia. In comparison with racemic bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action.

Levobupivacaine hydrochloride is a sodium channel blocker used as a long-acting local anaesthetic for epidural anesthesia. Levobupivacaine is the isomer of bupivacaine, with efficacy similar to that of bupivacaine with a reduced risk of cardiotoxicity.

 

Levobupivacaine hydrochloride COA:


Test Items
Specification Test Results
Description White or almost white crystalline powder White crystalline powder
Melting Point 191.0~193.0ºC 192ºC
Loss of drying ≤1.0% 0.5%
Heavy Metal ≤20ppm 15ppm
TLC Only one spot Only one spot
Assay ≥99.5% 99.91%
Conclusion It complies with the USP 32.

 

Application:
Levobupivacaine is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by Abbott under the trade name Chirocaine. Bupivacaine is an amide-type local anaesthetic. Although it blocks neuro transmission, its membrane stabilising action also affects the myocardium. This can cause fatal cardiotoxicity. As bupivacaine is widely used in surgery and obstetrics, attempts have been made to develop a safer long-acting local anaesthetic.

The bupivacaine molecule is a racemic compound. Levobupivacaine is the S-enantiomer of bupivacaine and is thought to have less cardiotoxic potential than the R-enantiomer. The pharmacokinetic parameters of levobupivacaine are similar to those of bupivacaine.

Levobupivacaine has been studied in surgical anaesthesia and for pain management. It can be used for local infiltration, epidural, intrathecal and peripheral nerve blocks. For epidural analgesia it can be given with clonidine. Double-blind comparisons of levobupivacaine and bupivacaine show that their anaesthetic effects are similar.


Our Advantage:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. High Quality: 
   1)Standard: Enterprise Standard 
   2)Purity: 99%
3. Varied Payment Terms: T/T Bank Transfer, Western Union, MoneyGram and Bitcoin 
4. Competitive price: We are manufacturer and can provide products with factory price.
5. Worldwide clients: 
   1)Professional service and rich experience make customers feel at ease.
   2)Market and goods feedback will be accepted.



  Levobupivacaine Hydrochloride


Basic Information: 
Synonyms: BUPIVACAINE HCL; (S)-Bupivacaine; LEVAMISOLHCLSALT; L-(-)-Bupivacaine; TIMTEC-BB SBB001337; LEVOBUPIVACAINE HCL; (S)-(-)-Bupivacaine; (S)-(-)-BUPIVACAINE HCL; bupicainehydrochloride(-); L-BUPIVACAINE HYDROCHLORIDE

Product Name: Levobupivacaine Hydrochloride
AS No.: 27262-48-2
Packing: 25kg/drum
M.F.: C18H29ClN2O
M.W.: 324.8887
Appearance: White crystalline powder




Additional Information:
product categories: Pharmaceutical raw materials; Active pharmaceutical ingredients
usage: Anesthetic; Na+ channel inhibitor.
Storage instructions: Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Packaging details: 25kg/drum, 1kg/foil bag
Delivery time: 1-2 days
Payment terms: T/T, western union, money gram, bitcoin



Description:
The hydrochloride salt of levobupivacaine, an amide derivative with anesthetic property. Levobupivacaine reversibly binds voltage-gated sodium channels to modulate ionic flux and prevent the initiation and transmission of nerve impulses (stabilizing neuronal membrane), thereby resulting in analgesia and anesthesia. In comparison with racemic bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action.

Levobupivacaine (rINN) is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine. It is the hydrochloride salt of levobupivacaine, an amide derivative with anesthetic property.

Levobupivacaine reversibly binds voltage-gated sodium channels to modulate ionic flux and prevent the initiation and transmission of nerve impulses (stabilizing neuronal membrane), thereby resulting in analgesia and anesthesia. In comparison with racemic bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action.

Levobupivacaine hydrochloride is a sodium channel blocker used as a long-acting local anaesthetic for epidural anesthesia. Levobupivacaine is the isomer of bupivacaine, with efficacy similar to that of bupivacaine with a reduced risk of cardiotoxicity.

 

Levobupivacaine hydrochloride COA:


Test Items
Specification Test Results
Description White or almost white crystalline powder White crystalline powder
Melting Point 191.0~193.0ºC 192ºC
Loss of drying ≤1.0% 0.5%
Heavy Metal ≤20ppm 15ppm
TLC Only one spot Only one spot
Assay ≥99.5% 99.91%
Conclusion It complies with the USP 32.

 

Application:
Levobupivacaine is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by Abbott under the trade name Chirocaine. Bupivacaine is an amide-type local anaesthetic. Although it blocks neuro transmission, its membrane stabilising action also affects the myocardium. This can cause fatal cardiotoxicity. As bupivacaine is widely used in surgery and obstetrics, attempts have been made to develop a safer long-acting local anaesthetic.

The bupivacaine molecule is a racemic compound. Levobupivacaine is the S-enantiomer of bupivacaine and is thought to have less cardiotoxic potential than the R-enantiomer. The pharmacokinetic parameters of levobupivacaine are similar to those of bupivacaine.

Levobupivacaine has been studied in surgical anaesthesia and for pain management. It can be used for local infiltration, epidural, intrathecal and peripheral nerve blocks. For epidural analgesia it can be given with clonidine. Double-blind comparisons of levobupivacaine and bupivacaine show that their anaesthetic effects are similar.


Our Advantage:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. High Quality: 
   1)Standard: Enterprise Standard 
   2)Purity: 99%
3. Varied Payment Terms: T/T Bank Transfer, Western Union, MoneyGram and Bitcoin 
4. Competitive price: We are manufacturer and can provide products with factory price.
5. Worldwide clients: 
   1)Professional service and rich experience make customers feel at ease.
   2)Market and goods feedback will be accepted.



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