China Recommend Steroid Powders/Injection Steroid liquid/Peptides/Sarms/Local anesthetics/Nootropics/Antidepressant/Health Care Supplement......
Product Name: AcitretinÂ
Synonyms: (all-e)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraen;6,8-nonatetraenoicacid,3,7-dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-4;all-trans-3,7-dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-2,4,6,8-nonatetra;all-trans-etretin;retinoidetretin;ro10-1670;(E)-9-(4-METHOXY-2,3,6-TRIMETHYLPHENYL)-3,7-DIMETHYL-2,4,6,8-NONATETRAENOIC ACID;etretinÂ
CAS: 55079-83-9Â
MF: C21H26O3Â
MW: 326.43Â
EINECS: 259-474-4Â
Product Categories: Active Pharmaceutical Ingredients;Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Retinoids;Intracellular receptor;API;Aromatics;Soriatane;Inhibitors
Melting point  228-230°CÂ
Storage temp.  2-8°C
Chemical Properties : Yellow Green Crystalline SolidÂ
Usage : A synthetic retinoid which is the major metabolite of etretinate .Â
Usage : antipsoriatic;binds to nuclear receptors that regulate gene transcription .
Acitretin Description
Acitretin is a second generation retinoid. It is taken orally, and is typically used for psoriasis. It is a metabolite of etretinate, which was used prior to the introduction of acitretin. They induce keratinocyte differentiation and reduce epidermal hyperplasia.
Acitretin is the least toxic systemic treatment for psoriasis. It is an oral retinoid of choice used in the treatment of severe resistant psoriasis. It binds to nuclear receptors that regulate gene transcription .
Acitretin was discontinued because it had a narrow therapeutic index as well as a long elimination half-life (t1/2=120 days), making dosing difficult. In contrast, acitretin's half-life is approximately 2 days .
Medical Application of Acitretin
Acitretin is an oral retinoid used in the treatment of severe resistant psoriasis. Because of the potential for problems and severe side effects it is generally used in only very severe cases of psoriasis that have been unresponsive to other treatments .
It binds to nuclear receptors that regulates gene transcription. They induce keratinocyte differentiation and reduce epidermal hyperplasia, leading to the slowing of cell reproduction. Acitretin is readily absorbed and widely distributed after oral administration. A therapeutic effect occurs after 2 to 4 weeks or longer .
Patients that have received the medication are advised against giving blood for at least 3 years due to the risk of birth defects .
Adverse effect
Acitretin is noted for the possibility of severe birth defects and should not be used by pregnant women or women planning to get pregnant within 3 years following the use of acitretin. Sexually active women of childbearing age who use acitretin should also use at least 2 forms of birth control concurrently. Men and women who use it shouldnot donate blood for 3 years after using it, because of the possibility that the blood might be used in a pregnant patient and cause birth defects. In addition, it may cause nausea, headache, itching, dry, red or flaky skin, dry or red eyes, dry or chapped lips, swollen lips, dry mouth, thirst, cystitis acne or hair loss .
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Antipsoriatic Active Pharmaceutical Ingredients Acitretin CAS 55079-83-9
China Recommend Steroid Powders/Injection Steroid liquid/Peptides/Sarms/Local anesthetics/Nootropics/Antidepressant/Health Care Supplement......
Product Name: AcitretinÂ
Synonyms: (all-e)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraen;6,8-nonatetraenoicacid,3,7-dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-4;all-trans-3,7-dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-2,4,6,8-nonatetra;all-trans-etretin;retinoidetretin;ro10-1670;(E)-9-(4-METHOXY-2,3,6-TRIMETHYLPHENYL)-3,7-DIMETHYL-2,4,6,8-NONATETRAENOIC ACID;etretinÂ
CAS: 55079-83-9Â
MF: C21H26O3Â
MW: 326.43Â
EINECS: 259-474-4Â
Product Categories: Active Pharmaceutical Ingredients;Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Retinoids;Intracellular receptor;API;Aromatics;Soriatane;Inhibitors
Melting point  228-230°CÂ
Storage temp.  2-8°C
Chemical Properties : Yellow Green Crystalline SolidÂ
Usage : A synthetic retinoid which is the major metabolite of etretinate .Â
Usage : antipsoriatic;binds to nuclear receptors that regulate gene transcription .
Acitretin Description
Acitretin is a second generation retinoid. It is taken orally, and is typically used for psoriasis. It is a metabolite of etretinate, which was used prior to the introduction of acitretin. They induce keratinocyte differentiation and reduce epidermal hyperplasia.
Acitretin is the least toxic systemic treatment for psoriasis. It is an oral retinoid of choice used in the treatment of severe resistant psoriasis. It binds to nuclear receptors that regulate gene transcription .
Acitretin was discontinued because it had a narrow therapeutic index as well as a long elimination half-life (t1/2=120 days), making dosing difficult. In contrast, acitretin's half-life is approximately 2 days .
Medical Application of Acitretin
Acitretin is an oral retinoid used in the treatment of severe resistant psoriasis. Because of the potential for problems and severe side effects it is generally used in only very severe cases of psoriasis that have been unresponsive to other treatments .
It binds to nuclear receptors that regulates gene transcription. They induce keratinocyte differentiation and reduce epidermal hyperplasia, leading to the slowing of cell reproduction. Acitretin is readily absorbed and widely distributed after oral administration. A therapeutic effect occurs after 2 to 4 weeks or longer .
Patients that have received the medication are advised against giving blood for at least 3 years due to the risk of birth defects .
Adverse effect
Acitretin is noted for the possibility of severe birth defects and should not be used by pregnant women or women planning to get pregnant within 3 years following the use of acitretin. Sexually active women of childbearing age who use acitretin should also use at least 2 forms of birth control concurrently. Men and women who use it shouldnot donate blood for 3 years after using it, because of the possibility that the blood might be used in a pregnant patient and cause birth defects. In addition, it may cause nausea, headache, itching, dry, red or flaky skin, dry or red eyes, dry or chapped lips, swollen lips, dry mouth, thirst, cystitis acne or hair loss .
 More products you may like
Tianeptine sodium CAS Â 30123-17-2
Tianeptine sulfate CAS : 1224690-84-9
Tianeptine (Tianeptine Free Acid ) CAS : 66981-73-5
Idra-21 CAS 22503-72-6
NSI-189 Free Base CAS 1270138-40-3
NSI-189 Phosphate CAS 1270138-41-4
9-fluorenol CAS 1689-64-1
Paroxetine hydrochloride  CAS 78246-49-8
Vilazodone Hydrochloride  CAS 163521-08-2
Vortioxetine Hydrobromide  CAS 960203-27-4
Levetiracetam  CAS : 102767-28-2
Parecoxib Sodium  CAS:198470-85-8
Atomoxetine Hydrochloride CAS 82248-59-7
Armodafinil CAS 112111-43-0
CDP-Choline Base CAS 987-78-0
Duloxetine HCl  CAS 136434-34-9
Fluoxetine Hydrochloride  CAS 56296-78-7
Phenibut  CAS 1078-21-3
Antipsoriatic Active Pharmaceutical Ingredients Acitretin CAS 55079-83-9
Model NO.: 55079-83-9
CAS: 55079-83-9
Appearance: Yellow Green Crystalline Solid
Express Way: EMS, FedEx, TNT, DHL, Hkems
Alias: Acitretin
Trademark: WHSO
Transport Package: 1kg/25kg/Package
Specification: 99%
Origin: China
HS Code: 121425246
Model NO.: 55079-83-9
CAS: 55079-83-9
Appearance: Yellow Green Crystalline Solid
Express Way: EMS, FedEx, TNT, DHL, Hkems
Alias: Acitretin
Trademark: WHSO
Transport Package: 1kg/25kg/Package
Specification: 99%
Origin: China
HS Code: 121425246
Antipsoriatic Active Pharmaceutical Ingredients Acitretin CAS 55079-83-9